Key for health in your tooth: Exploring dental stem cells

“Now you can ensure healthy future simply with your falling tooth!”

Perfect health and long life is everyone’s lucid dream. In the present era, where the science has found cure to almost every other disease, still many common disorders such as diabetes, cancer, congenital anomalies, organ failure, neural disorders, etc. are the major challenges to the scientists and medical practitioners.

Recently, stem cell therapy has emerged as a viable technique in this area. Stem cells are the undifferentiated cells which has potential to give rise to more specialized cells and tissue lineage (nerve, muscle, gland, etc.). The various sources for stem cells in a human body are umbilical cord, bone marrow, adipose tissue, dental structures, etc.

Dental mesenchymal stem cells (DMSCs) have been widely studied and used successfully in regeneration of damaged tissues and treatment of various disorders. Ideally, DMSCs banking should be done in early age group (5-25 years) to obtain maximum amount of viable stem cells. DMSC can be easily harvested from teeth and other structures and can be stored for long. The whole procedure of DMSC banking is simple and can be carried out in any dental clinic under local anesthesia and good asepsis. Several parents have undergone stem cell banking for their children to ensure their safe future. With ongoing research and continuous efforts, stem cells can change the perspective of regenerative therapy.

Potential applications of stem cells

Congenital anomalies (cleft lip and palate)

Blood disorders (thalassemia, sickle cell disease)

Skeletal disorders (Muscular dystrophy, bone regeneration)

Eye (corneal, limbal regeneration)

CNS & Neuromuscular disorders (Parkinsons, stroke, Alzheimer’s, epilepsy)

Cardiac defects (myocardial infarction)

Endocrine disorders (diabetes, thyroid, etc.)

Cancer

Regeneration of damaged tissues (kidney, nerve, diabetic foot, teeth)

 

 

Sources of DMSCs

Dental pulp

Periodontal tissues

Deciduous teeth

Dental follicle (tooth bud)

 

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